• We've completed one of the biggest updates to our forums in years and have pushed the update live! New forum structure that's all inclusive, prefix system categorizes topics per game title. More thread options such as articles, questions, deep dives, etc. Read more in the pinned thread!

Virus Virus Analysis: Uroboros

The magnum opus of Albert Wesker, the Uroboros Virus is the closest any virus has gotten to unlocking the potential of Progenitor to achieve immortality.
The Virus was named after Ouroboros (Uroboros is an alternative spelling), a symbol with origins in 14th century BC Egypt. Ouroboros is the symbol’s Greek name (which means “tail food"), and it depicts a serpent devouring it's own tail. It represents unity, infinity, and cycles in mysticism. In alchemy, it is linked to the magnum opus and philosopher’s stone, and represents self-perfection through transmutation (accumulating in the formula for immortality).

Overview


The creation of Uroboros was envisioned in 2006, after Wesker determined to usurp Oswell Spencer's ambitions, and development began shortly thereafter with the discovery of the Progenitor Virus by the TRICELL corporation. Wesker's original plans of mass extinction and replacing humanity fused with Spencer's goal of an evolved humanity. Unlike Spencer's plans, Wesker ignored the rejection rates of Progenitor adaption, allowing speedy development (only three years), as anyone not equal to himself had no place in his new world. In fact, no one else might have even survived.
Spencer envisioned a virus identical to Uroboros, except his version would be more forgiving with adaption (after all, he would be infected himself). He sought to achieve this with T, and approved of G for the same reason.
After Wesker was killed by Chris Redfield and Sheva Alomar, the BSAA took down TRICELL and presumably destroyed all samples of Uroboros they could. However, Alex Wesker had a sample of the virus recovered, and she used it in bioweapons experiments. After the death of Alex, Uroboros may now be extinct.

Effects


Uroboros is the most "pure" of all the Progenitor Viruses. It is less lethal than modern Progenitor, yet still lethal enough to kill billions. It effectively restores the virus' ability to evolve human hosts, something all other viruses have fallen short of. It is also extraordinarily virulent, and if a sufficient quantity of the virus were released into the upper tropopause, all humans living on the entire planet would quickly be infected.
While Uroboros was created directly from Progenitor, t-Veronica and the G-Virus were used as a reference, to achieve what they failed to do. The only known outside agent introduced to the virus was Jill Valentine's t-Virus antibodies, which lessened toxicity just enough to allow hosts like Wesker to survive infection.
The main difference between Progenitor and Uroboros was that the latter eliminated random mutation (at least in human hosts), resulting in two consistent results: adaption and rejection.

Adaption


Once Uroboros enters the host, it develops a “core” (a bright orange organ) from which sprouts viral pustules the size of snakes. These pustules feed on organic tissue, and begin devouring the host from the inside out, like the snake devouring it's own tail (Ouroboros).
If a host has excellent genes like Albert or the ancient Ndipaya, they are able to metabolize the pustules after they begin growing, and they are completely absorbed into the body. Dosage must be precise, as overdosing can either prevent the pustules from being subdued, or simply prolong the process.
After the virus is absorbed by the body, the host becomes a stable super human similar to Progenitor Humans. Uroboros Humans would presumably have abilities equal to Albert Wesker, like enhanced speed and strength, and almost supernatural regenerative capabilities. Unlike Albert, they would also cease aging and require no serum to stabilize the virus. They would be as close as you can get to literal immortals. Whether or not they would be able to breed or acquire enhanced intelligence like Progenitor Humans or Mary Gray is not known (see the “Super Human” section of Virus Analysis: Tyrant for more info). They would have the characteristic eye mutation seen in adapters, and may be able to generate and control pustules at will.

Rejection


If the host lacks adaptable genes, the pustules will not be suppressed, but will consume the body, leaving the few remnants of the host as a vehicle for the pustules to seek more food. The resulting mass of pustules (simply called “Uroboros”, similar to how t-Virus hosts are called Tyrants, G-Virus hosts are called G, etc.) will continue to feed on both living and dead biomatter, increasing in size, and will possibly merge with other Uroboros masses. These masses are not mutant hosts, but are actually the virus itself, growing and spreading. Uroboros is incapable of random mutations in human hosts.
These creatures have very limited intelligence, but operate in tandem when connected to a single core, which acts as a brain and source of activity. Some will develop multiple cores. The body of an Uroboros can dismantle in order to transverse small cracks.
Like Zombies and many other B.O.W.s, the only way to kill such masses is to destroy it's brain - the core. But it's location in the center of the body makes this difficult, and the pustules are extremely durable and prone to regenerate. However, the pustules are extremely sensitive to heat, and can be temporarily burned away to reveal the core.
Individual pustules not attached to a core are of little threat, and will likely die on their own. Larger Uroboros creatures can spawn small independent clumps of pustules capable of distracting or ensnaring prey.

A host who has partially adaptable genes will begin to become an Uroboros Human, but will quickly degenerate into an especially volatile Uroboros creature. One such host was encountered and destroyed by Chris and Sheva. This creature, called “Uroboros Mkono”, had multiple cores and a large limb capable of attacking from a distance. Mkono is Swahili for “arm” (in reference to it's limb).

A Uroboros creature that has absorbed many corpses will grow into a giant, tree-like monster called “Uroboros Aheri”. Excella Gionne, after being infected with Uroboros by Wesker, became one such creature. If the Uroboros Virus was released on the word, the surface of the planet would be covered by Aheri. Aheri is Swahili for “better” (in reference to it's superiority over Mkono) or for “end” or “limit” (in reference to it being the final stage of the Uroboros lifecycle).

Special Hosts


While the results of live infection are supposed to be consistent, several abnormalities exist in three particular hosts.

Albert Wesker, as an Uroboros adapter, was able to control the pustules after infection and prevent them from consuming him. However, he overdosed, resulting in a prolonged bonding period. His skin blackened and pustules consumed his arms. These pustules wrapped around shards of metal, which Albert used as dangerous slashing weapons. Had he not been killed in the volcano, he would presumably repress the growths eventually and become an Uroboros Human.

The peculiarities in Neil and Alex were owing to semi-compatible genes like the Mkono host and a prior infection with t-Phobos. These two are covered more in the t-Phobos Analysis.

Only one type of irregular mutant created by Uroboros has ever been encountered: the Reapers. Cockroaches are famous for their vitality - it is commonly said they would continue to thrive after a nuclear apocalypse, and can survive decapitation and other such wounds. As such, the vitality these creatures possess have allowed them to mutate favorably from Uroboros. They have not only grown immensely like t-Virus infected arthropods, but after some time in a cocoon, have become entirely new bipedal creatures. This demonstrates the ability of Progenitor to create new life, which has appeared most prominently in G, C, and Uroboros.
Reapers have extreme regenerative abilities thanks to Uroboros, being able to regrow limbs in seconds, but the exposed, core-like organs they have serve as weak points. They expel a gas capable of blinding prey. They are named for their scythe-like blades.

Revenants


Like G, injection of Uroboros into deceased hosts results in rudimentary animation, resulting in the creation of Revenants. Like live host infection, infection begins with the development of a core. However, a lack of living tissue prevents the development of new biomatter (aka pustules). Instead, organic matter surrounding the core is repaired and "converted" into Uroboros tissue, becoming black and sticky, underneath the dead skin. When the skin is peeled away, Revenants are revealed to simply be human shaped pustule masses unable to generate new material and spread. Like live hosts, destroying the core is the only means of destroying Revenants.
Alex Wesker created an army of Revenants to hunt down Natalia Korda. The limbs of multiple humans were stitched and assembled, and the nature of Uroboros in organic material allowed them to fuse and operate in tandem. Metallic parts were stitched in as well to function as weapons. They greatly resembled marionettes, and were named after a type of undead spirit.

Splashers are Revenants with large, pus filled sacs for arms (with vestigial hands). They splash this pus at targets to obscure vision. These sacs are either related to Uroboros cores, the slime mold cysts seen on Afflicted, or limbs mutated by t-Phobos (the charred remains of Gabe had an identically shaped arm). The latter two explanations would be due to the fact the parts Alex used were from previous experiments.

Slingers are comprised of legs attached to a horribly misshapen torso (if it can even be called that). The core is located on the chest, while the right arm is a boney stub. The left arm is a disfigured, parasite-like body the Slinger slings at prey, which explodes on impact. Using Uroboros' regenerative potential, it can then regrow this "arm".

The deadliest type of Revenant, the Durga is named after a multi-armed Hindu deity. It is comprised of legs and a torso attached at the waist by a large core. The torso's arms are bound upwards, and attach to a large mass of human heads/faces. This gruesome "head" is surrounded by many attached arms that hang down and cover it's core. From the front extends a hardened Uroboros-composed tentacle that ends in a claw, invulnerable to gunfire and strong enough to pick up or crush an adult human.
 

mert20004

Mert_BIO_6
I really wished re5 focused more on uroboros and had more monsters related to it.

Cause of the dumb racism complaints; the game couldnt make use of its full potential.

I'm glad it got used more in rerev2 though.
 
If someone could help me out--there's something I've never quite understood about this one. It's easy to understand how infection works by injection: simply inject the virus into a human host, then wait for it to make its "judgement." But how exactly does it infect people in its physical form, the form that Wesker intended to spread across the planet? Do the tentacles find their way onto a human and collectively absorb themselves into the body, then lay dormant for some time until the virus makes its decision? I imagine this is how it works, but I've never fully gotten it.
 
Last edited:

A. Wesker

Fortes Fortuna Adiuvat
That's a good question, also how do the Uroboros missiles even work? surely they wouldn't just blow up since fire is it's biggest weakness. Now I remember that scene of David killing the Engineers in Covenant, I like to think it might have looked like this

LtvNCSI.gif


After the virus is absorbed by the body, the host becomes a stable super human similar to Progenitor Humans. Uroboros Humans would presumably have abilities equal to Albert Wesker, like enhanced speed and strength, and almost supernatural regenerative capabilities. Unlike Albert, they would also cease aging and require no serum to stabilize the virus. They would be as close as you can get to literal immortals. Whether or not they would be able to breed or acquire enhanced intelligence like Progenitor Humans or Mary Gray is not known (see the “Super Human” section of Virus Analysis: Tyrant for more info). They would have the characteristic eye mutation seen in adapters, and may be able to generate and control pustules at will.

This is good stuff, and this is what always made me doubt Wesker fully adapted to Uroboros, back then I assumed he didn't because he got two extra doses of progenitor, but it was confirmed he actually did. Either way, he became a slow and easy to kill monster, not much of an upgrade. I think the gameplay of 5 near the end doesn't seem to be very in tune with aspects of the lore.
 
That's a good question, also how do the Uroboros missiles even work? surely they wouldn't just blow up since fire is it's biggest weakness. Now I remember that scene of David killing the Engineers in Covenant, I like to think it might have looked like this

LtvNCSI.gif

's


This is good stuff, and this is what always made me doubt Wesker fully adapted to Uroboros, back then I assumed he didn't because he got two extra doses of progenitor, but it was confirmed he actually did. Either way, he became a slow and easy to kill monster, not much of an upgrade. I think the gameplay of 5 near the end doesn't seem to be very in tune with aspects of the lore.
My guess is that, after being dispersed onto the planet's troposphere, the missiles would somehow automatically break themselves apart and release the virus without having to blow up. Then it would spread using the wind currents (westerlies). The missiles were definitely not designed to reach the Earth's surface and blow up because, as you mention, that could potential cause problems for the virus to stay alive; and it would also make it much harder (slower) for the virus to spread across the globe.

In terms of how it infects people... my guess is that infection would take place immediately after coming in contact with the tentacles (the virus in its physical form). It would then make its "judgement" in one of two ways: 1.) the tentacles would somehow do the DNA selection process while squirming around on your body. If you are compatible, they'll soak into you and you will become a superhuman; but if you're incompatible, the tentacles would just tear into you and eat your body, and eventually turn you into an Uroboros monster; or 2.) the tentacles in mass would somehow (still wondering how) soak themselves into the body and lay dormant as the virus undergoes the DNA selection process. From there, either you are one of the lucky few to become superhuman or one of the unfortunate many (most) to become a miserable mess of spaghetti and meatballs.

That image is just what I imagine it to be like. Christ, imagine what that outbreak would look like. Especially given the fact that the vast majority of the population would NOT BE compatible! The entire WORLD would literally become a bowl of spaghetti and meatballs!

1246

I really wish they had been a bit more in-depth with this one and how it works.
 
Last edited:
EDIT/UPDATE

So a few days ago, I found this "timeline" created by RE Podcast that sort of explains it. Apparently, as soon as the virus comes into contact with a host, it immediately starts to dig away into the body. This is the DNA selection process. If it accepts you, then the tentacles get absorbed into you and you become superhuman; and if it rejects you, then it just amplifies by turning your cells into more tentacles, which eventually turn you into a complete bowl of spaghetti and meatballs. ?
 
Top Bottom